In Vitro Diagnostics

In Vitro Diagnostics

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IVD Fluorescent Dyes

In vitro diagnostics (IVD) are tests on samples such as blood, tissue or urine that have been taken from the animal or human body. IVD can detect diseases or other conditions and can be used to monitor a person’s overall health to help cure, treat, or prevent diseases. IVD enables to provide rapid test results, to simultaneously perform multiple tests, to detect customizable specific markers, to easily record data, and to quickly repeat the test for confirm. IVD may also be used in precision medicine to identify patients who are likely to benefit from specific treatments or therapies. BioActs offers a series of FSD Fluor dyes for effective IVD analysis.

FSD Fluor™ NHS ester

In vitro diagnostics analyze samples that taken from the human body such as blood or tissue. In vitro diagnostics enable to detect specific disease or other conditions and to simultaneously provide multiple test results. In vitro diagnostics can be used to find specific medicine or therapy for patients whom to benefit from the treatment. In vitro diagnostics may also be used to monitor a person’s overall health to help cure, treat, or prevent diseases. BioActs provides a variety of in vitro diagnostic (IVD) materials such as fluorescent polystyrene beads, magnetic nanoparticles, dyes, MRSA and MRAB detection kit, PCR kit, immuno staining kit, organ clearing kit, etc.

Quick link (Cat.#)	FSD series	EXmax (nm)	EMmax (nm	Spectrally similar dyes
KOSC1002	FSD Fluor™ 488	495	519	Alexa Fluor 488, FAM, Cy2
KOSC1003	FSD Fluor™ 555	554	565	Alexa Fluor 555, DyLight 549, Cy3, ATTO 550
KOSC1001	FSD Fluor™ 594	591	617	Alexa Fluor 594, DyLight 594
KOSC1315	FSD Fluor™ 647	651	667	Alexa Fluor 647, Cy5, ATTO 647N, DyLight 650
KOSC1515	FSD Fluor™ 680	679	696	Alexa Fluor 680, Cy5.5, DyLight 680, IRDye 680
KOSC1702	FSD Fluor™ 750	749	774	Alexa Fluor 750, DyLight 755, Cy7, IRDye 750
POSC1803	FSD Fluor™ 800	774	790	Cy7.5, DyLight 800, IRDye 800

Fluorescent Polystyrene Beads
Flamma® PS bead series are fluorescent spherical particles in the colloidal size made up of high-grade polystyrene (PS) doped with our proprietary dyes. Polystyrene beads are not cytotoxic, and they diffuse minimally from the injection site and persist for long periods in nerve cells. Our fluorescent beads display excellent optical properties yet negligible photobleaching under the intense excitation for fluorescence microscopy. The intense fluorescence and spherical shape of Flamma® PS bead series enable to generate stronger signals with small amount of probes in many tracing experiments. To decrease nonspecific binding and provide additional functional groups for conjugation, exteriors of PS bead are equipped with carboxylic acids. These pendent carboxylic acids allow them suitable for covalent coupling of proteins and other amine-containing biomolecules by using water-soluble coupling reagents. BioActs provides various sizes of Flamma® PS bead series (0.1 – 0.5 μm) in order to meet the diverse needs of our customer, and sizes specified in the product names are nominal bead diameters. These effective fluorescent PS beads can be utilized in a variety of applications such as neuronal tracers, cellular antigen markers, cell tracers, and the standardization reagents for flow cytometry. Due to their high fluorescence intensity, Flamma® PS bead series are suitable for the many nanoparticle based diagnostic tests, including tracking particles and cells, tracing fluid dynamics, discriminating the size dependence of uptake or transport in vivo. Although limited sizes of our fluorescent beads are available, we can prepare custom-sized particles, custom-dyed or custom-surface modifications orders upon request. Please contact our custom service for further information.
Flamma® Deep Red

PS Bead 0.1um	PS Bead 0.2um

Quick link (Cat.#)	Series	*Ex (nm)**	*Em (nm)**	Bead size	Functionality	Solids
PSC7003	Flamma® Deep Red PS Bead 0.1 um	645	665	0.1 μm	COOH	2%
PSC7001	Flamma® Deep Red PS Bead 0.2 um	645	665	0.2 μm	COOH	2%
PSC7002	Flamma® Deep Red PS Bead 0.5 um	645	665	0.5 μm	COOH	2%

Magnetic Nanoparticles
BioActs Magnetic Nanoparticles are coated with silica polymer, affording biocompatibility, and can be used in a wide range of biological and biomedical fields such as cell separation, drug delivery, DNA extraction and protein purification. The strong magnetism of particles allows excellent dispersion, fast reaction and separation, low background signal. In order to conjugate with biomolecules such as DNA, RNA, protein, antibody, etc., the surface of magnetic nanoparticle is functionalized with alcohol, amine and carboxylic acid. BioActs Magnetic Nanoparticles can be utilized in medical diagnostic, medical research, and therapeutic purpose.
Magnetic Nanoparticle

PS Bead 0.1um	PS Bead 0.2um	PS Bead 0.5um

Quick link (Cat.#)	Series	Surface modification	Diameter
MNP1000	Silica Carboxy Magnetic Nanoparticles	Carboxy ( -COOH)	200 nm - 300 nm
MNP2000	Silica Amine Magnetic Nanoparticles	Amine ( -NH₂)	200 nm - 300 nm
MNP3000	Silica Hydroxy Magnetic Nanoparticles	Hydroxy ( -OH)	200 nm - 300 nm