FSD Fluor™ 750 NHS ester

FSD Fluor™ 750 NHS ester is a cutting-edge, amine-reactive near-infrared (NIR) fluorescent dye developed by BioActs. This next-generation dye offers superior optical properties compared to spectrally similar fluorophores, making it an ideal choice for a wide range of biochemical and biological analytical applications. Applications of FSD Fluor™ 750 include invitro imaging (Conjugated primary and secondary antibodies serve as molecular probes), In Vivo NIR Imaging (Optimized for labeling antibodies, peptides, proteins, and ligands), amine-modified oligonucleotide labeling in molecular biology, protein tagging and cellular imaging in cell biology and in medical imaging for deep tissue penetration for non-invasive diagnostics. FSD Fluor™ 750 is compatible with most common fluorescence imaging systems, including:Confocal microscopes with 750 nm laser excitation; Flow cytometers with red laser (633 nm) excitation; and In vivo imaging systems with NIR capabilities.

Some key features are:
Exceptional Brightness: With an extinction coefficient of ≥200,000 cm?¹M?¹, FSD Fluor™ 750 delivers outstanding fluorescence intensity after binding to biomolecules.
Optimal Spectral Properties: Excitation/Emission maxima at 751/774 nm, similar to Alexa 750, Cy7, IRDye 750, and DyLight 755.
Versatile Applications: Ideal for single-molecule detection, fluorescence correlation spectroscopy, and fluorescence polarization measurements.
Tissue Penetration: Emission in the NIR region allows for deep tissue imaging.

Advantages Over Similar Dyes:
Enhanced Stability: Dye-protein conjugates show improved photostability.
Superior Brightness: Up to 1.5x brighter than spectrally similar dyes in protein conjugates.
Reduced Background: Lower non-specific binding, resulting in improved signal-to-noise ratios.

 

Background
FSD Fluor™ is a new generation of dye series with superb fluorescence intensity and high quantum yield comparing to traditional dyes. The fluorescence intensity after binding to biomolecules such as antibody, nucleotide, and protein maintains still excellent, FSD Fluor™ series is ideal for variety of biochemical and biological analytical applications with a less amount of dye conjugate. FSD Fluor™ series equipped with a variety of reactive groups and covers the full fluorescence spectral range from UV to NIR, hence the series is ideal for any applications in fluorescence spectroscopies and biological studies. With superior fluorophores and the wide spectral range, FSD Fluor™ dyes are suitable for every filter and are designed to meet the requirements for complex detection in the field of life science research.

Key Benefits: 

• Superior brightness: up to 30% brighter than leading competitors, enabling detection fo low-abundance targets. 
• Excellent Stability: Maintains high fluorescence intensity after bioconjugation
• Versatile Applications: Ideal for antibody labeling, nucleic acid detection, and protein studies
• Optimized for Single-Molecule Detection: Perfect for fluorescence correlation spectroscopy and polarization measurements
• Higher quantum yield comparing to traditional dyes
• Equipped with variety of reactive group
• Covering the full fluorescence spectral range from visible to NIR
• Enhanced Sensitivity: Detect targets with greater accuracy, even at low concentrations
• Reduced Background: Higher signal-to-noise ratio for clearer images and more reliable data
• Cost-Effective: Achieve superior results with less dye, maximizing your research budget

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