Silica Carboxy Magnetic Nanoparticles
Cat. No. List below
Description
BioActs Silica Coated Magnetic Nanoparticles are advanced, multifunctional particles designed for a wide range of biomedical and research applications. These nanoparticles combine the unique properties of superparamagnetic iron oxide cores with the versatility and biocompatibility of silica coating, offering a powerful tool for various scientific and diagnostic purposes.
Magnetic Properties:
Type of Magnetization: Superparamagnetic
Magnetization: > 110 EMU/g
Time for magnetic attachment: < 10s
Its high magnetization (> 110 EMU/g) ensures rapid response to external magnetic fields and its superparamagnetic nature prevents particle aggregation in the absence of a magnetic field. The silica coating provides a biocompatible surface, reducing potential toxicity, and enhances colloidal stability in physiological conditions. Its capable of binding > 100 µg of antibody per mg of particles, allowing for efficient biomolecule immobilization.
Thwe hydroxy-modified surface allows for efficient conjugation with biomolecules, proteins, antibodies, drugs, and nucleotides.
Its applications include cell and protein separation, immunoassays, nucleic acid extraction, drug delivery, magnetic resonance imaging (MRI) contrast enhancement, and biosensing and diagnostics
BioActs Silica Coated Magnetic Nanoparticles represent a significant advancement in nanomaterial technology, offering researchers and clinicians a versatile and powerful tool for a wide range of applications. Their unique combination of superparamagnetic properties, biocompatible surface, and high functionalization capacity makes them ideal for cutting-edge research in fields such as biomedicine, diagnostics, and targeted therapies. The hydroxy surface modification provides additional opportunities for tailoring the nanoparticles to specific research needs, enhancing their utility in diverse scientific applications.
Unique Advantages:
1. Customizable Surface: Hydroxy groups enable various coupling chemistries for attaching different biomolecules
2. Size Optimization: 200-300 nm diameter balances cellular uptake efficiency and magnetic responsiveness
3. Stability: Silica coating protects the iron oxide core from degradation and oxidation
4. Uniform Dispersion: Aqueous suspension ensures even particle distribution for consistent results
5. Scalability: Suitable for both small-scale research and large-scale industrial applications
6. Hydroxyl Surface: Provides excellent hydrophilicity and potential for further functionalization
Magnetic Properties:
Type of Magnetization: Superparamagnetic
Magnetization: > 110 EMU/g
Time for magnetic attachment: < 10s
Its high magnetization (> 110 EMU/g) ensures rapid response to external magnetic fields and its superparamagnetic nature prevents particle aggregation in the absence of a magnetic field. The silica coating provides a biocompatible surface, reducing potential toxicity, and enhances colloidal stability in physiological conditions. Its capable of binding > 100 µg of antibody per mg of particles, allowing for efficient biomolecule immobilization.
Thwe hydroxy-modified surface allows for efficient conjugation with biomolecules, proteins, antibodies, drugs, and nucleotides.
Its applications include cell and protein separation, immunoassays, nucleic acid extraction, drug delivery, magnetic resonance imaging (MRI) contrast enhancement, and biosensing and diagnostics
BioActs Silica Coated Magnetic Nanoparticles represent a significant advancement in nanomaterial technology, offering researchers and clinicians a versatile and powerful tool for a wide range of applications. Their unique combination of superparamagnetic properties, biocompatible surface, and high functionalization capacity makes them ideal for cutting-edge research in fields such as biomedicine, diagnostics, and targeted therapies. The hydroxy surface modification provides additional opportunities for tailoring the nanoparticles to specific research needs, enhancing their utility in diverse scientific applications.
Unique Advantages:
1. Customizable Surface: Hydroxy groups enable various coupling chemistries for attaching different biomolecules
2. Size Optimization: 200-300 nm diameter balances cellular uptake efficiency and magnetic responsiveness
3. Stability: Silica coating protects the iron oxide core from degradation and oxidation
4. Uniform Dispersion: Aqueous suspension ensures even particle distribution for consistent results
5. Scalability: Suitable for both small-scale research and large-scale industrial applications
6. Hydroxyl Surface: Provides excellent hydrophilicity and potential for further functionalization
Specifications
- Surface modification: Hydroxy
- Composition: Silanized Iron Oxide
- Type of Magnetization: Superparamagnetic
- Magnetiztion: > 110 EMU/g
- Concentration: 20 mg/mL
- Appearance: Aqueous suspension
- Diameter: 200 nm ~ 300 nm
- Time for attached to magnet: < 10s
- Amount of antibody labeling: > 100 µg/mg
- Storage conditions: 4 ℃
Table 1. Magnetic Nanoparticle series list
| Quick link (Cat.#) | Series | Surface modification | Diameter |
| MNP1000 | Silica Carboxy Magnetic Nanoparticles | Carboxy ( -COOH) | 200 nm - 300 nm |
| MNP2000 | Silica Amine Magnetic Nanoparticles | Amine ( -NH2) | 200 nm - 300 nm |
| MNP3000 | Silica Hydroxy Magnetic Nanoparticles | Hydroxy ( -OH) | 200 nm - 300 nm |
Overview
BioActs Magnetic Nanoparticles are coated with silica polymer, affording biocompatibility, and can be used in a wide range of biological and biomedical fields such as cell separation, drug delivery, DNA extraction and protein purification. The strong magnetism of particles allows excellent dispersion, fast reaction and separation, low background signal. In order to conjugate with biomolecules such as DNA, RNA, protein, antibody, etc., the surface of magnetic nanoparticle is functionalized with alcohol, amine and carboxylic acid.
BioActs Magnetic Nanoparticles can be utilized in medical diagnostic, medical research, and therapeutic purpose.

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