Anti-FGF21 Rabbit Polyclonal Antibody
Anti-FGF21 Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB113713 |
| Size | ：100 uL |
| Protein full name | ：Fibroblast growth factor 21 |
| Synonym | ：FGF-21, FGF21, UNQ3115, PRO10196 |
| Immunogen | ：KLH conjugated Synthetic peptide corresponding to Mouse FGF21 |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Subcellular location | ：Secreted |
| Uniprot ID | ：Q9NSA1 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human | 1: 1000-1: 2000 | liver |
Description
Fibroblast growth factor 21 (FGF21), a member of the FGF superfamily, has emerged as an important metabolic regulator. FGF21 is produced in the liver, adipocytes and skeletal muscle and regulates glucose, energy and lipid metabolism. FGF21 is a stress-responsive hepatokine which is induced in the liver as a response to injury, regeneration, hepatocarcinogenesis and during kidney dysfunction. FGF21 is primarily metabolized in the kidney and renal secretion is the major route of FGF21 elimination. Its plasma levels increase according to the decline in renal function in patients with chronic and acute renal dysfunction.
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Immunohistochemistry analysis of paraffin-embedded human liver using FGF21 (GB113713) at dilution of 1: 2000 |
