Anti-MYL1 Rabbit Polyclonal Antibody
Product#: SB-GB112474
$560.00
Availability:
Ships in 1-2 Weeks
Anti-MYL1 Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB112474 |
| Size | ：100 uL |
| Protein full name | ：Myosin light chain 1/3, skeletal muscle isoform |
| Synonym | ：MLC1/MLC3, MLC1F/MLC3F, Myosin light chain alkali 1/2, Myosin light chain A1/A2, Myl1, Mylf, |
| Immunogen | ：Recombinant protein corresponding to Mouse Myl1 |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Subcellular location | ：Cytoskeleton |
| Predicted MW. | ：21 kDa |
| Observed MW. | ：21 kDa |
| Uniprot ID | ：P05977, P02600 |
| Long Term Storage | ：-20 ℃ or below |
| Shipping Condition | ：Dry Ice |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse | 1: 2000-1: 4000 |
skeletal muscle |
| IHC | Mouse, Rat | 1: 500-1: 1000 | skeletal muscle |
| IF | Mouse, Rat | 1: 500-1: 1000 | skeletal muscle |
Description
Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.
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Western blot analysis of Myl1 (GB112474) at dilution of 1: 4000 Lane 1: Mouse skeletal muscle tissue lysate Lane 2: Mouse skeletal muscle tissue lysate Lane 3: Mouse skeletal muscle tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using Myl1 (GB112474) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using Myl1 (GB112474) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse skeletal muscle using Myl1 (GB112474) at dilution of 1: 1000
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Antigen Characterization
- Type: Primary
- Application: ELISA,Western Blot,IHC,IF
- Species: Human, Mouse
- Recombinant: Yes
Human Diseases
- Cardiovascular Diseases: Associated with cardiac muscle function and heart conditions.
- Skeletal Muscle Disorders: Implications in muscle contraction abnormalities.
- Hypertension: Linked to signaling pathways affecting vascular smooth muscle contraction
Cellular Signaling Pathways
- Calcium Signaling: MYL1 is involved in calcium-induced contraction mechanisms in muscle cells.
- RhoA Pathway: Plays a role in actin-myosin interaction during smooth muscle contraction.
- Angiotensin II Signaling: Influences vasoconstriction through myosin light chain phosphorylation
References
- Database, Rat Genome. MYL1 (Myosin, Light Chain 1) - Rat Genome Database, rgd.mcw.edu/rgdweb/report/gene/main.html?id=1598796.
- Tissue Expression of Myl1 - Summary - The Human Protein Atlas, Human Protein Atlas, www.proteinatlas.org/ENSG00000168530-MYL1/tissue.
- MYL1 Myosin Light Chain 1 [Homo Sapiens (Human)] - Gene - NCBI.” National Center for Biotechnology Information, U.S. National Library of Medicine, www.ncbi.nlm.nih.gov/gene?Cmd=DetailsSearch&Db=gene&Term=4632.
- MYL1 Myosin, Light Polypeptide 1 [Mus Musculus (House Mouse)] - Gene - NCBI.” National Center for Biotechnology Information, U.S. National Library of Medicine, www.ncbi.nlm.nih.gov/gene?Cmd=DetailsSearch&Db=gene&Term=17901.
- MYL1 Polyclonal Antibody.” Elabscience, www.elabscience.com/p-myl1_polyclonal_antibody-271442.html.
Aliases for MYL1 Gene
- GeneCards Symbol: MYL1 2
- Myosin Light Chain 1 2 3 5
- Myosin Light Chain 1/3, Skeletal Muscle Isoform 2 3 4
- Myosin, Light Polypeptide 1, Alkali; Skeletal, Fast 2 3
- Myosin, Light Chain 1, Alkali; Skeletal, Fast 2 3
- Myosin Light Chain Alkali 1/2 3 4
- Myosin Light Chain A1/A2 3 4
- MLC1F/MLC3F 3 4
- MLC1/MLC3 3 4
- MLC1/3 2 3
- MLC1F 2 3
- MLC3F 2 3
- MLC-1 2 3
- MLC1 2 3
- A1 Catalytic 3
- A2 Catalytic 3
- MYOFTA 3
