Anti-Artemin Rabbit Polyclonal Antibody
Anti-Artemin Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB113614 |
| Size | ：100 uL |
| Protein full name | ：Artemin |
| Synonym | ：Artn, Enovin, EVN, NBN, Neublastin, Neurotrophic factor |
| Immunogen | ：Recombinant protein corresponding to Mouse Artemin |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Subcellular location | ：Secreted |
| Uniprot ID | ：Q6AYE8 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| IHC | Rat | 1: 1000-1: 2000 |
cerebellum, striatum |
Description
This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma.
 |
Immunohistochemistry analysis of paraffin-embedded rat cerebellum using Artemin (GB113164) at dilution of 1: 2000 |
 |
Immunohistochemistry analysis of paraffin-embedded rat striatum using Artemin (GB113164) at dilution of 1: 2000 |
Aliases for Artemin Gene
