Nocardamin (desferrioxamine E) is a cyclic siderophore consisting of three units of 5-succinylated-1-aminohydroxyamino-pentane belonging to the ferrioxamine group. Nocardamin is produced by species of Nocardia1,2), Chromobacterium3), Pseudomonas4), and several other Streptomyces species5,6). It is known that desferrioxamines act as siderophres and have important clinical applications7). In addition, nocardamin stimulates secondary metabolite formation and morphological differentiation in various actinomycete strain8) .
Origin: Streptomyces sp.
CAS Registry Number: 26605-16-3
Appearance: off-white solid
Molecular Formula/ Weight: C27H48N6O9=600.71
Purity: 95>% by HPLC
Solubility: Sol. DMSO, hot MeOH, water Insol. Chloroform, EtOAc, Hexane
Handling and Storage: Store at -20℃.
References:
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Zlhner H. et al. Pathol Microbiol . 25, 708-736 (1962).
Tam TF. et al. Curr Med Chem . 10, 983-995 (2003).