Anti-TATA binding protein Rabbit Polyclonal Antibody
General information
| Cat. No. | :SB-GB113810 |
| Size | :100 uL |
| Protein full name | :TATA-box-binding protein |
| Synonym | :GTF2D, GTF2D1, SCA17, TATA-binding factor, TATA-box factor, TATA sequence binding protein, TBP, TF2D, TFIID |
| Immunogen | :KLH conjugated Synthetic peptide corresponding to Mouse TBP |
| Isotype | :IgG |
| Purity | :Affinity purification |
| Predicted MW. | :35 kDa |
| Observed MW. | :35 kDa |
| Uniprot ID | :P29037 |
| Storage | :Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | :PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 200-1: 500 |
testis, ovary |
The TATA binding protein (TBP) is a transcription factor that binds specifically to a DNA sequence TATA box. This DNA sequence is found about 25-30 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II. This antibody recognize human TBP with MW 40 kDa and mouse/rat Tbp with MW 34 kDa.
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Western blot analysis of TBP (GB113810) at dilution of 1: 500 |