Anti Human TR alpha mouse monoclonal antibody (H2804)
Product#: FNK-PP-H2804-00
$501.52
Availability:
Ships in 1-2 Weeks
Anti Human TR alpha mouse monoclonal antibody (H2804)
TR alpha: Thyroid Hormone Receptor alpha
General information
| Cat. No. | ：FNK-PP-H2804-00 |
| Size | ：100 ul |
| Antigen Species | ：Human |
| Host Species | ：Mouse |
| Cross Reactivity | ：Human/ Rat |
| Purification | ：Ammonium sulfate fractionation. |
| Clone No | ：H2804 |
| Lot. | ：A-1 |
| Concentration | ：1 mg/mL |
| Ig Class | ：G2a |
| Nomenclature | ：NR1A1 |
| Application | ：ELISA : 0.1 ug/mL (A450=0.5) ：Western Blot : 1 ug/mL ：Non reducing Western Blot : 3 ug/mL ：Immunohistochemistry : 20-50 ug/mL |
| Specificity |
：This antibody specifically recognizes human TR alpha and cross reacts with mouse and rat TR alpha.
This antibody does not recognize human TR beta |
| Storage | ：Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | ：Physiological saline with 0.1% NaN3 as a preservative |
| Genbank | ：M24748 |
Description
Thyroid hormone receptor alpha (TRa, THRA; NR1A1) is a member of nuclear hormone receptors. The ligands for TRa are the thyroid hormones, which exist in two forms: T4 (3,5,3',5'-tetraiodo-L-thyronine) and T3 (3,5,3'- tri-iodo-L-thyronine). TRa plays critical roles in the differentiation, growth, metabolism and physiology of a wide variety of tissues. The major partners of TRs are the RXRs, which strongly enhance their ability to bind to specific DNA sequences and contribute to the specificity of action of TR.
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human TR alpha (2-51 aa) .
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Aliases for THRA Gene
- Thyroid Hormone Receptor Alpha 2 3 4 5
- NR1A1 2 3 4
- Thyroid Hormone Receptor, Alpha (Erythroblastic Leukemia Viral (V-Erb-A) Oncogene Homolog, Avian) 2 3
- Nuclear Receptor Subfamily 1 Group A Member 1 3 4
- V-ErbA-Related Protein 7 3 4
- C-ErbA-Alpha 3 4
- ERBA1 3 4
- THRA1 3 4
- THRA2 3 4
- EAR-7 3 4
- EAR7 3 4
- ERBA 2 3
- AR7 2 3
- Thyroid Hormone Receptor, Alpha (Avian Erythroblastic Leukemia Viral (V-Erb-A) Oncogene Homolog) 2
- Thyroid Normone Nuclear Receptor Alpha Variant 1 3
- Thyroid Hormone Receptor Alpha 1 3
- Triiodothyronine Receptor 3
- EAR-7.1/EAR-7.2 2
- ERBA-Related 7 3
- C-ERBA-1 3
- C-ErbA-1 4
- ERB-T-1 3
- CHNG6 3
- THRA3 2
- THRA 5
