Anti Human TR beta 1 mouse monoclonal antibody (H3825A)
Product#: FNK-PP-H3825A-00
$501.52
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Anti Human TR beta 1 mouse monoclonal antibody (H3825A)
TR beta1: Thyroid Hormone Receptor beta1
General information
| Cat. No. | ：FNK-PP-H3825A-00 |
| Size | ：100 ul |
| Antigen Species | ：Human |
| Host Species | ：Mouse |
| Cross Reactivity | ：Human |
| Purification | ：Ammonium sulfate fractionation. |
| Clone No | ：H3825A |
| Lot. | ：A-1 |
| Concentration | ：1 mg/mL |
| Ig Class | ：G2a |
| Nomenclature | ：NR1A2 |
| Application | ：ELISA (0.1 ug/mL), Western Blot (1 ug/mL) |
| Specificity |
：This antibody specifically recognizes human TR beta 1 but does not recognize TR beta 2 and TR alpha.
Not yet tested in other species. |
| Storage | ：Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | ：Physiological saline with 0.1% NaN3 as a preservative |
| Genbank | ：X04707 |
Description
Thyroid hormone receptor beta (TRb, THRB; NR1A2) is a member of nuclear hormone receptors. The ligands for TRb are the thyroid hormones, which exist in two forms: T4 (3,5,3',5'-tetraiodo-L-thyronine) and T3 (3,5,3'- tri-iodo-L-thyronine). TRb plays critical roles in the differentiation, growth, metabolism and physiology of a wide variety of tissues. The major partners of TRs are the RXRs, which strongly enhance their ability to bind to specific DNA sequences and contribute to the specificity of action of TR.
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant TR beta 1 (2-100 aa).
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Aliases for THRB Gene
- Thyroid Hormone Receptor Beta 2 3 4 5
- NR1A2 2 3 4
- THR1 2 3 4
- Thyroid Hormone Receptor, Beta (Erythroblastic Leukemia Viral (V-Erb-A) Oncogene Homolog 2, Avian) 2 3
- Nuclear Receptor Subfamily 1 Group A Member 2 3 4
- Oncogene ERBA2 2 3
- ERBA2 3 4
- THRB1 2 3
- THRB2 2 3
- GRTH 2 3
- Thyroid Hormone Receptor, Beta (Avian Erythroblastic Leukemia Viral (V-Erb-A) Oncogene Homolog 2) 2
- Avian Erythroblastic Leukemia Viral (V-Erb-A) Oncogene Homolog 2 2
- Thyroid Hormone Nuclear Receptor Beta Variant 1 3
- Generalized Resistance To Thyroid Hormone 2
- Pituitary Resistance To Thyroid Hormone 2
- Thyroid Hormone Receptor Beta 1 2
- Thyroid Hormone Receptor, Beta 2
- C-ERBA-BETA 3
- C-ErbA-Beta 4
- ERBA-BETA 2
- C-ERBA-2 3
- C-ErbA-2 4
- PRTH 3
- THRB 5
