Anti Human ROR gamma mouse monoclonal antibody (H6437)
Product#: FNK-PP-H6437-00
$501.52
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Anti Human ROR gamma mouse monoclonal antibody (H6437)
ROR gamma: RAR-related orphan receptor gamma
General information
| Cat. No. | ：FNK-PP-H6437-00 |
| Size | ：100 ul |
| Antigen Species | ：Human |
| Host Species | ：Mouse |
| Cross Reactivity | ：Human |
| Purification | ：Ammonium sulfate fractionation. |
| Clone No | ：H6437 |
| Lot. | ：A-1 |
| Concentration | ：1 mg/mL |
| Ig Class | ：G2a |
| Nomenclature | ：NR1F3 |
| Application | ：ELISA : 0.3 ug/mL (A450=0.5) ：Western Blot : 1 ug/mL |
| Specificity |
：This antibody specifically recognizes human ROR gamma but does not recognize ROR alpha and beta.
Not yet tested in other species. |
| Storage | ：Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | ：Physiological saline with 0.1% NaN3 as a preservative |
| Genbank | ：U16997 |
Description
Retinoic acid-related orphan receptor gamma (RORg, TOR, RORC; NR1F3) is a member of orphan nuclear receptor. RORg is expressed in muscle, thymus, testis, pancreas, prostate, heart and liver. RORg plays a role in thymocyte development and homeostasis. RORs bind to DNA as monomers on half-site elements with 5' A/T-rich extension. An N-terminal isoform of RORg, RORgt, has been shown to be specifically expressed in the thymus.
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human ROR gamma (2-30 aa) .
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Aliases for RORC Gene
- RAR Related Orphan Receptor C 2 3 5
- NR1F3 2 3 4
- RORG 2 3 4
- RZRG 2 3 4
- Nuclear Receptor Subfamily 1 Group F Member 3 3 4
- RAR-Related Orphan Receptor C 2 4
- Nuclear Receptor ROR-Gamma 3 4
- Nuclear Receptor RZR-Gamma 3 4
- TOR 2 3
- RAR-Related Orphan Nuclear Receptor Variant 2 3
- Retinoid-Related Orphan Receptor Gamma 3
- Retinoid-Related Orphan Receptor-Gamma 4
- Retinoic Acid-Binding Receptor Gamma 3
- RZR-GAMMA 3
- IMD42 3
- RORC 5
