Anti Human LXR beta mouse monoclonal antibody (K8917)
Anti Human LXR beta mouse monoclonal antibody (K8917)
LXR beta: Liver X Receptor beta
General information
| Cat. No. | ：FNK-PP-K8917-00 |
| Size | ：100 ul |
| Antigen Species | ：Human |
| Host Species | ：Mouse |
| Cross Reactivity | ：Human |
| Purification | ：Ammonium sulfate fractionation. |
| Clone No | ：K8917 |
| Batch | ：A2F1 |
| Concentration | ：1 mg/mL |
| Ig Class | ：G2a |
| Nomenclature | ：NR1H2 |
| Application | ：ELISA : 0.1 ug/mL ：Western Blot : 2 ug/mL ：Non-reducing Western Blot : 2 ug/mL |
| Specificity | ：This antibody specifically recognizes human LXR beta but does not recognize human LXR alpha. This antibody does not cross react with rat LXR beta. Not yet tested in other species. |
| Storage | ：Lyophilized samples are stable for twelve months when held at 2 - 8 C. Upon reconstitution, the antibody can be stored at 2 - 8 C up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | ：Lyophilized from phosphate-buffered saline (PBS) containing 5% Trehalose as a stabilizer. |
| Genbank | ：U07132 |
Description
Liver X receptor beta (LXRb, UR, NER, RIP15, OR -1; NR1H2) is a member of orphan nuclear receptor. LXRb is expressed in a wide variety of tissues (heart, liver, kidney, brain, testis, ovary, adrenal, uterus, prostate, vagina, lung, spleen). LXRs play important role in expression of ABC transporters. The protein is expressed as a 50 kDa nuclear form. LXRb forms heterodimer with RXR.
Reconsitution
Reconstitute with desired volume of distilled water. Reconstitution in 0.1 ml of distilled water yields an antibody concentration of 1mg/ml. Please note reconstituted solution will contain original PBS and 5% Treharose (see Formulation).
Reference
- Watanabe Y, et al., Nuclear Receptor, 1: 1, 2003.
- Pavan L, et al., Endocrinology, 145(10): 4583-91, 2004.
Aliases for NR1H2 Gene
- Nuclear Receptor Subfamily 1 Group H Member 2 2 3 4 5
- Ubiquitously-Expressed Nuclear Receptor 2 3 4
- NER 2 3 4
- Oxysterols Receptor LXR-Beta 3 4
- Nuclear Receptor NER 3 4
- LXR-B 2 3
- NER-I 2 3
- RIP15 2 3
- LXRB 3 4
- UNR 3 4
- Nuclear Receptor Subfamily 1, Group H, Member 2 2
- Steroid Hormone-Nuclear Receptor NER 3
- Nuclear Orphan Receptor LXR-Beta 3
- Liver X Nuclear Receptor Beta 3
- Liver X Receptor-Beta 2
- Liver X Receptor Beta 4
- LX Receptor Beta 3
- NR1H2 5
- LXRb 2
