(-)-Epigallocatechin Gallate
Product#: FNK-E-5737
$274.07
Availability:
Ships in 1-2 Weeks
(-)-Epigallocatechin Gallate
Cat. No. FNK-E-5737
Size 1 g
Store 4oC
m.p. 215～216℃
M.W. 458.37
Purity ＞90％（HPLC）
Chemical Names :
- (-)-Epigallocatechin gallate
- EGCG
- 989-51-5
- Epigallocatechin gallate
- Epigallocatechin 3-gallate
Molecular Weight 458.375 g/mol
XLogP3 1.2
Hydrogen Bond Donor Count 8
Hydrogen Bond Acceptor Count 11
Rotatable Bond Count 4
Exact Mass 458.085 g/mol
Monoisotopic Mass 458.085 g/mol
Topological Polar Surface Area 197 A^2
Heavy Atom Count 33
Formal Charge 0
Complexity 667
Isotope Atom Count 0
Defined Atom Stereocenter Count 2
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
Description
Epigallocatechin Gallate is a phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to cells. It is under study as a potential cancer chemopreventive agent. (NCI)
(-)-epigallocatechin 3-gallate is a gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin. It has a role as an antineoplastic agent, an antioxidant, a Hsp90 inhibitor, a neuroprotective agent and a plant metabolite. It is a gallate ester, a polyphenol and a member of flavans. It derives from a (-)-epigallocatechin.
Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
Epigallocatechin gallate has been investigated for the treatment of Hypertension and Diabetic Nephropathy.
