Cycloaspeptide A, 5 mg
Product#: FNK-BLK-0420-5mg
$285.03
Availability:
Ships in 1-2 Weeks
Cycloaspeptide A
Cat No: FNK-BLK-0420-5mg
Product ID and Size
| Cat No. | Description | Size | Link |
| FNK-BLK-0420-100ug | Cycloaspeptide A | 100μg |  |
| FNK-BLK-0420-1mg | Cycloaspeptide A | 1mg | |
| FNK-BLK-0420-5mg | Cycloaspeptide A | 5mg | |
Description
Cycloaspeptides were isolated from Aspergillus sp. NE-451), Penicillium ribeum2), Tricothecium strain3) and other microorganisms, and cyclic peptide antibiotics. Cycloaspeptide A and D exhibited moderate activity (IC50 3.5 and 4.7 microg/ml, respectively) against Plasmodium falciparum.4) Cycloaspeptide A showed low cytotoxicity towards human lung fibroblasts with IC50 > or = 1000 microM.5) Cycloaspeptides are solubilized in methanol or benzene, but insoluble in water.
Origin: Gliocladium sp.
CAS Registry Number: 109171-13-3
CA Index Name: N-Methylcyclo[L-Tyr-2- amino*benzoyl-L-Ala-N-methyl-LPhe-L-Leu-]
Appearance: White crystalline
Molecular Formula/ Weight: C36H43N5O6=641.77
Melting Point: 275-277°C
Purity: >95.0% by HPLC
Solubility: Sol. 1mg/ml ethanol, methanol, DMSO
Handling and Storage: Store at -20℃.
References:
- Kobayashi et. al., Chem Pharm Bull. 35, 1347-1352 (1987).
- P. W. Dalsgaard, J. Nat. Prod. 67, 878-881 (2004).
- P, Lewer, et. al., J. Nat. Prod. 69, 1506-1510 (2006).
- P. W. Dalsgaard, et. al., J. Antibiot. (Tokyo). 58, 141-144 (2005).
- G. Schmeda-Hirschmann, et. al., Z. Naturforsch [C]. 63, 383-388 (2008)
