Anti-Medaka Vitellogenin IgG, HRP Conjugate
Product#: FNK-MVD33-HRP
$412.85
Availability:
Ships in 1-2 Weeks
Anti-Medaka Vitellogenin IgG, HRP Conjugate
DiagnoCine offers excellent antibodies for VITELLOGENIN: CARP, KILLFISH, MEDAKA (CLONE d3-3 & f10-2 & HRP-LABELED), and RED SEA BREAM
These antibodies are excellent tools for researchers studying the early development of egg-laying vertebrates and invertebrates, apolipoproteins, yolk proteins, N-terminal lipid transports, vesicle trafficking, and juvenile hormone feedback loop mechanisms.
(ELISA kit and Standard kit are also available).
VITELLOGENIN | VTG antibodies have excellent quality and this highly pure antibody can be adapted for Western Blots, ELISA, Immunohistochemistry, Immunofluorescence research with optimization.
General information
| Cat. No. | ：FNK-MVD33-HRP |
| Size | ：0.5 mL |
| Presentation | ：Supplied as a iquid in 0.01M Tris, 0.15M NaCl, 1% BSA, pH 7.5 |
| Components | ：Standard(100 ng / ml ) 0.5 ml + dilution buffer 1 ml |
| Immunogen Source | ：Purified medaka vitellogenin |
| Appearance | ：Clear liquid |
| Application | ：ELISA (1:100 - 1:1000), Western blot (1:100 - 1:5000) |
| Long Term Storage | ：–20℃ or below |
| Shipping Condition | ：Dry Ice |
| Warning | ：For research use only. |
Description
Vitellogenin, the egg yolk precursor protein, is induced by estrogens. On the other hand, environmental estrogens are known to disrupt endocrine system in animals. Recently, vitellogenin has proven to be an ideal marker for enviromental estrogen.
Antigen Characterization
- Type: Primary
- Application: ELISA (Enzyme-Linked Immunosorbent Assay),Western Blot, Immunohistochemistry, Immunofluorescence
- Species: Japanese Medaka
- Recombinant: Yes
Human Diseases
- Endocrine Disruption: Vitellogenin levels in fish serve as biomarkers for assessing exposure to environmental estrogens, which can have implications for human health due to the endocrine-disrupting effects of certain chemicals.
- Reproductive Health Issues: Elevated vitellogenin levels may indicate potential reproductive health risks associated with endocrine disruptors that can affect both aquatic and terrestrial organisms, including humans.
Cellular Signaling Pathways
- Estrogen Signaling Pathway: Vitellogenin is primarily regulated by estrogen, which binds to estrogen receptors, activating downstream signaling pathways that lead to vitellogenin synthesis in the liver.
- Nuclear Receptor Pathway: Involves the interaction of estrogen receptors with specific DNA sequences to modulate gene expression related to vitellogenin production.
- Apoptosis Pathway: Disruption of normal vitellogenin signaling can lead to altered cell survival and apoptosis in reproductive tissues
Aliases for Medaka Vitellogenin Gene
- VTG
- Vitellogenin precursor
- Yolk protein precursor
References
- TECO® Reach Medaka Vitellogenin Elisa.” DiaPharma, 23 Sept. 2024, diapharma.com/product/teco-reach-medaka-vitellogenin-elisa/.
- Magentech. “Medaka Vitellogenin Standard for Elisa Assay.” Your Store, diagnocine.com/Product/Medaka-Vitellogenin-Standard-for-ELISA-Assay/52412.
- Carp Vtg, Elisa, 480-Test, www.goldstandarddiagnostics.us/home/products/rapid-test-kits/vitellogenins/carp-vtg-elisa-480-test/.
- Vitellogenin.” Vitellogenin - an Overview | ScienceDirect Topics, www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/vitellogenin.
Note
Since assay conditions vary, the optimum dilution should be determined for particular applicarion.
