Anti-ARMET/ARP Rabbit Polyclonal Antibody
Anti-ARMET/ARP Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB113576 |
| Size | ：100 uL |
| Protein full name | ：Mesencephalic astrocyte-derived neurotrophic factor |
| Synonym | ：Arginine-rich protein, ARMET, ARP, MANF, Protein ARMET |
| Immunogen | ：Recombinant protein corresponding to Mouse ARMET/ARP |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Predicted MW. | ：20 kDa |
| Observed MW. | ：20 kDa |
| Uniprot ID | ：Q9CXI5, P0C5H9 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 500-1: 1000 |
testis, pancreas |
Description
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
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Western blot analysis of ARMET (GB113576) at dilution of 1: 1000 |
Aliases for ARMET Gene
