Anti Mouse GLP/ Ehmt1 mouse monoclonal antibody (B0422)
General information
| Cat. No. |
:FNK-PP-B0422-00 |
| Size |
:100 ul |
| Antigen Species |
:Human |
| Host Species |
:Mouse |
| Cross Reactivity |
:Human |
| Purification |
:Ammonium sulfate fractionation |
| Clone No |
:B0422 |
| Lot. |
:A-1 |
| Concentration |
:1 mg/mL |
| Ig Class |
:G2a |
| Epitope |
:- |
| Application |
:ELISA ( 0.1 ug/mL),Western Blot (0.5 ug/mL), Immunohistochemistry (5 ug/mL) |
| Specificity |
:This antibody specifically recognizes mouse GLP and cross reacts with human GLP.
Not yet tested in other species
|
| Storage |
:Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form |
:Physiological saline with 0.1% NaN3 as a preservative. |
| Genbank |
:AB205007 |
Description
Histone H3 Lys 9 (H3-K9) methylation is a crucial epigenetic mark for transcriptional silencing. G9a is the major mammalian H3-K9 methyltransferase that targets euchromatic regions and is essential for murine embryogenesis. There is a single G9a-related methyltransferase in mammals, called GLP/EuHMTase1.
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant mouse GLP (134-234 aa).
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Reference
1. Tachibana M. et al., Genes Dev, 1; 19(7): 815-26, 2005
Aliases for EHMT1 Gene
- Euchromatic Histone Lysine Methyltransferase 1 2 3 5
- Eu-HMTase1 2 3 4
- KMT1D 2 3 4
- Euchromatic Histone-Lysine N-Methyltransferase 1 3 4
- Histone-Lysine N-Methyltransferase EHMT1 3 4
- Histone H3-K9 Methyltransferase 5 3 4
- Lysine N-Methyltransferase 1D 3 4
- EHMT1 Intronic Transcript 1 2 3
- G9a-Like Protein 1 3 4
- H3-K9-HMTase 5 3 4
- EUHMTASE1 3 4
- KIAA1876 2 4
- GLP1 3 4
- GLP 3 4
- Histone-Lysine N-Methyltransferase, H3 Lysine-9 Specific 5 3
- Euchromatic Histone Methyltransferase 1 2
- BA188C12.1 2
- EC 2.1.1.- 4
- EHMT1-IT1 3
- FLJ12879 2
- FLJ40292 2
- FP13812 3
- KLEFS1 3
- EHMT1 5