This antibody recognizes lacto-N-fucopentaose I (LNFP I: Fucβ1–2Galβ1–3GlcNAcβ1–3Galβ1–4Glc) on a glycolipid / glycoprotein. R-17F epitopes are expressed on undifferentiated human induced pluripotent stem (iPS) / embryonic stem (ES) cells but not on human embryonal carcinoma (EC) cells nor on differentiated human iPS/ES cells.
Description
New specific antibody for human iPS/ES cells iPSelector (Anti-Human LNFP I, Mouse Monoclonal)
iPSelector is a mouse monoclonal antibody recognizes for lacto-N-fucopentaose I (LNFP I) raised against human iPS cells.
LNFP I is the sugar chain expressed in undifferentiate state human iPS or ES cells then this antibody can be used as a marker for undiffrentiated human iPS or ES cells.
Moreover, this antibody has a function for cytotoxic effect by binding to undifferentiated human iPS or ES cells.
Therefore this antibody is beneficial for removing undifferentiated human iPS or ES cells.
This antibody has been commercialized under a license from Ritsumeikan University.