SARS-COV-2 N protein full length (England)

Cat. No.: FNK-BCL-CON-FG02

Size: 100μg

Storage: 4℃ (for long term store at -20℃, do not repeatedly freeze and thaw)


Introduction:

Based on over 10 years biotechnology research experience, Beacle developed SARS-COV-2 related products. SARS-COV-2 is a virus having  an envelope structure. Several proteins including Spike (S) proteins are displayed on the envelope, and in the envelope  nucleus (N) protein make a complex with its RNA gene.   The infection is revealed to start form the binding of S protein’s SB domain to ACE2 receptors of host cells and subsequent viral enters into host cells through endocytosis.   Viral RNA is then released into cells by the aid of S protein’s S2 domain through  membrane fusion system. N protein is the most abundant protein of SARS-COV-2 and highly immunogenic,  and infected human often shows high antibody to N proteins. N protein is composed of three domains, called N terminus domain (NTD) related with RNA binding, C terminus domain (CTD) related with formation of complexes, and liner region of the two domains which is related with phosphorylation.  Many vaccines are developed against SARS-COV-2 infection, and all of them utilizes S protein as the target molecule.




Specifications:

Host cell: E. Coli

Appearance: solution (1 M NaCl, Tris-HC, pH 8.0）

Affinity: all proteins bind to each specific antibody

Quantity: 100μg/100μL

Purity: refer to SDS-PAGE below

Application: standard, antibody-detecting ELISA, and other