Demethoxycurcumin
Product#: FNK-2400283
$397.98
Availability:
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Demethoxycurcumin
Cat. No.: : FNK-2400283
Feature:
- CAS Number : 22608-11-3
- Molecular Weight : 338.35
- Molecular Formula : C20H18O5
- Pack size: 10 mg
- Store: Store at 2-10°C in a dry and dark place.
- Purity: (HPLC) ≥98％
Product description
- Demethoxycurcumin (DMC) is a natural demethoxy derivative of curcumin and one of the main active ingredients in curcumin. It is more stable than curcumin in physiological media and displays various biological activities.
Properties
- Molecular formula: C20H18O5
- Molecular weight: 338.35 g/mol
- CAS number: 22608-11-3
- Appearance: Likely a yellow powder (specific appearance not mentioned)
- Purity: ≥98% (HPLC)
- Solubility: Soluble in DMSO (≥10 mg/mL), ethanol, and 0.5 M NaOH
Application and usage
- Used as an analytical standard in research related to curcuminoids
- Employed in studies investigating antioxidant, anti-inflammatory, and anticancer activities
- Utilized in food science and natural product research
- Potential applications in the development of pharmaceuticals and nutraceuticals
Safety and handling
- Store at 2-8°C, protected from light
- Use appropriate personal protective equipment when handling
- Avoid inhalation and contact with skin and eyes
- Follow standard laboratory safety practices for chemical compounds
Involved human diseases
- Potential benefits in cancer treatment and prevention
- Possible applications in neurodegenerative diseases, particularly Alzheimer's disease
- May be beneficial in treating vascular injuries and inflammatory conditions
- Displays antibacterial activity against Mycobacterium tuberculosis
Involved cell signaling pathways
- Activates AMPK and inhibits eIF4E-bp3
- Inhibits STAT3 activation and increases caspase 3 activity
- Downregulates ROS-related signaling
- Inhibits phosphorylation of tau proteins
- Downregulates PI3K/Akt and ERK1/2 signaling
- Modulates iNOS pathway and decreases NO production
