Benanomicin B
Product#: FNK-02968
$598.00
Availability:
Ships in 24 hours
Benanomicin B
Specifications
Code No.: FNK-02968
CAS#: 116249-66-2
Molecular Formula: C39H42N2O18
Molecular Weight: 826.761
Source: Actinomadura sp.MH193-16F4
Appearance: Dark red powder
Purity: > 90%(HPLC)
Long Term Storage: at -20 °C
Solubility: HCl salt is soluble in H2O, DMSO, DMF, MeOH. Poorly soluble in acetone, CHCl3. Insoluble in hexane.
* The CAS# of the free form of Benanomicin B is shown above. The salt form ratio of this batch is as follows. HCO2H salt form / salt-free from = a.1/6.
CAS#: 116249-66-2
Molecular Formula: C39H42N2O18
Molecular Weight: 826.761
Source: Actinomadura sp.MH193-16F4
Appearance: Dark red powder
Purity: > 90%(HPLC)
Long Term Storage: at -20 °C
Solubility: HCl salt is soluble in H2O, DMSO, DMF, MeOH. Poorly soluble in acetone, CHCl3. Insoluble in hexane.
* The CAS# of the free form of Benanomicin B is shown above. The salt form ratio of this batch is as follows. HCO2H salt form / salt-free from = a.1/6.
Application Notes
Benanomicin B is isolated from the culture filtrates of Actinomadura sp. MH193-16F4.1,2 It shows excellent activities against a wide range of fungi including Candida, Cryptococcus and Saccharomyces.1,4 Benanomicin B also inhibited infection of human T-cells with human immunodeficiency virus (HIV-1) at 10~100 μg/mL and inhibited syncytium formation induced by HIV-1 at 10~100 μg/mL.3 The antifungal and anti HIV-1 activities of benanomicins and their analogues have been studied.4
References
- New antifungal antibiotics, benanomicins A and B from an actinomycete. Takeuchi T, et al. J Antibiot. 1988 41(6) 807-811.
- The structures of new antifungal antibiotics, benanomicins A and B. Gomi S, et al. J Antibiot. 1988 41(8) 1019-1028.
- New antifungal antibiotics, benanomicins A and B inhibit infection of T-cell with human immunodeficiency virus(HIV) and syncytium formation by HIV. Hoshino H, et al. J Antibiot. 1989 42(2) 344-346.
- Antifungal and antiviral activities of benanomicins and their analogues. Kondo S, et al. J Antibiot. 1991 44(11) 1228-1236.
Related Products
| Infection Related | Name | Product Code | Link |
|---|---|---|---|
| Anti-HIV-Ⅰ | Benanomicin A | FNK-02966 |  |
| Benanomicin B | FNK-02968 | Current Link | |
| Anti-MRSA, Anti-VRE | Bottromycin A2 | FNK-00592 | |
| Anti-Gram Positive / Negative Bacteria |
Althiomycin | FNK-14660 | |
| Cyclamidomycin | FNK-01541 | |
|
| Negamycin (HCl) | FNK-14662 | |
|
| Anti-Gram Positive Bacteria | Bottromycin A2 | FNK-00592 | |
| Anti-Respiratory Infectious Bacteria | Forphenicinol | FNK-09637 | |
| Acid-Fast Bacillus Growth Suppression | Minosaminomycin | FNK-02872 | |
| Antifungal | Benanomicin A | FNK-02966 | |
| Benanomicin B | FNK-02968 | Current Link | |
| Bacterial Protein Synthesis Inhibitor | Althiomycin | FNK-14660 | |
| Minosaminomycin | FNK-02872 | |
|
| Negamycin (HCl) | FNK-14662 | |
|
| Pneumocystis pneumonia suppression |
Benanomicin A | FNK-02966 | |
