:VEGFA, MVCD1, VEGF, VPF, vascular endothelial growth factor A
Immunogen
:KLH conjugated Synthetic peptide corresponding to Mouse VEGFA
Isotype
:IgG
Purity
:Affinity purification
Subcellular location
:Secret
Predicted MW.
:25 kDa
Observed MW.
:43 kDa
Uniprot ID
:P15692, Q00731, P16612
Storage
:Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
:PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
Application
Applications
Species
Dilution
Positive Tissue
WB
Human, Mouse, Rat
1: 500-1: 1000
brain, liver , kidney
Description
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 and Neopilsulfate heparan RP -1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a ance signaling pathway need on need for motor body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
Western blot analysis of VEGFA (GB11034B) at dilution of 1: 500