Anti-Topoisomerase I Rabbit Polyclonal Antibody
Product#: SB-GB112458
$560.00
Availability:
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Anti-Topoisomerase I Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB112458 |
| Size | ：100 uL |
| Protein full name | ：DNA topoisomerase 1 |
| Synonym | ：Top1, Top-1, NUP98 fusion gene, Type I DNA topoisomerase, TopoisomeraseI |
| Immunogen | ：Recombinant protein corresponding to Mouse Topoisomerase I |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Predicted MW. | ：91 kDa |
| Observed MW. | ：100 kDa |
| Uniprot ID | ：P11387 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Human | 1: 500-1: 1000 |
HeLa, MCF7, SW480, K562 |
Description
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
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Western blot analysis of Top1 (GB112458) at dilution of 1: 1000 Lane 1: HeLa cell lysate Lane 2: MCF7 cell lysate Lane 3: SW480 cell lysate |
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Western blot analysis of Top1 (GB112458) at dilution of 1: 1000 Lane 1: HeLa cell lysate Lane 2: K562 cell lysate |
Aliases for TOP1 Gene
- GeneCards Symbol: TOP1 2
- DNA Topoisomerase I 2 3 4 5
- Topoisomerase (DNA) I 2 3
- DNA Topoisomerase 1 3 4
- Scl-70 Antigen 2 3
- Type I DNA Topoisomerase 3
- EC 5.99.1.2 49
- EC 5.6.2.1 4
- TOPI 3
