Anti-Coplanar PCB #118

Product#: FNK-ACPM118AS

$412.85

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Anti-Coplanar PCB #118 (Mouse monoclonal antibody)

General information

Cat. No.

：FNK-ACPM118AS

Size

：1.0 mL

Antigen

：PCB #118-KLH conjugate

Host Animal

：Mouse

Isotype

：IgG₁

Purification

：This antibody was isolated from culture supernatant of hybridoma by Protein G affinity chromatography.

Purity

：>80% by SDS-PAGE

Concentration

：0.1 mg/mL

Appearance

：Clear liquid

Storage

：Short term, 4℃, Long term, -20℃, Avoid freeze thaw cycles

Shipping Condition

：Dry Ice

Cross Reactivity

3,3',4,4',-TCB	(#77)	17.8
3,4,4',5,-TCB	(#81)	< 3.0
3,3',4,4',5,-PeCB	(#126)	< 3.0
3,3',4,4',5,5'-HxTCB	(#169)	< 0.1
2,3,3',4,4'-PeCB	(#105)	2.5
2,3,4,4',5-PeCB	(#114)	3.4
2,3',4,4',5-PeCB	(#118)	100
2',3,4,4',5-PeCB	(#123)	< 0.1
2,3,3',4,4',5-HxCB	(#156)	7.2
2,3,3',4,4',5'-HxCB	(#157)	< 0.1
2,3;,4,4',5,5'-HxCB	(#167)	< 0.1
2,3,3',4,4',5,5'-HpCB	(#189)	< 0.1
Compounds that show no reaction up to 10 ppm Acenaphtene, Acenaphtherene, Anthracene, Benzo(a)anthracene, Benzo(a)pyrene, Benzo(b)fluoranthene, Benzo(ghi)perylene, Benzo(k)fluoranthene, Chrysene, Dibenzo(ah)anthracene, Fluoranthene, Hexachlorobenze, Indeno(123cd)pyne, Napthalene, Phennthrene Pyrene, Hexachlorobenze, Biphenyl, 1,2-dichlorobenzene, 3,4-dichloroaniline, 3,4-dichloroanisole, 3,4--dichloronitrobenzene, 3,4-dichlorophenol, 3,4-dichlorotoluene, 1,2,3-trichlorobenzene, 3,4,5-trichloroaniline, 3,4,5-trichlorophenol, 2,3,7,8-TCDD, 2,3,7,8-TCDF Note: Cross reactivity may be slightly different under each assay condition.

Preservative

：0.1% Sodium azide

Presentation

：Supplied as a liquid in 0.01M Tris, 0.15M NaCl, 0.1% Sodium azide, pH 7.5

Human Diseases

Linked to chronic inflammatory diseases such as cardiovascular disease, type 2 diabetes, and obesity.
Elevated liver enzyme levels and chloracne reported in populations with exposure.
Possible carcinogenic effects leading to various cancers.

Cellular Signaling Pathways

Aliases for PCB 118 Gene

References

PCB-118 (Compound).” Exposome, exposome-explorer.iarc.fr/compounds/946.
PCB No. 118.” PCB No. 118 | CAS 31508-00-6 | LGC Standards, www.lgcstandards.com/DE/en/PCB-No-118/p/DRE-C20011800.
Author links open overlay panelDevrim Kaya a b, et al. “A Comparative Evaluation of Anaerobic Dechlorination of PCB-118 and Aroclor 1254 in Sediment Microcosms from Three PCB-Impacted Environments.” Journal of Hazardous Materials, Elsevier, 3 Aug. 2017, www.sciencedirect.com/science/article/abs/pii/S0304389417305940.
Ruggeri, Rosaria, et al. “Polychlorinated Biphenyl Congeners PCB 118 and PCB 126 Induce Upregulation PD-L1 Expression in Human Thyrocytes through Aryl Hydrocarbon Receptor (AHR) Pathways.” Endocrine Abstracts, Bioscientifica, 2 Sept. 2022, www.endocrine-abstracts.org/ea/0084/ea0084ps2-06-56.