Anti-C-MYC Rabbit Polyclonal Antibody
Anti-C-MYC Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB113748 |
| Size | ：100 uL |
| Protein full name | ：Myc proto-oncogene protein |
| Synonym | ：bHLHe39, c Myc, c-Myc, MRTL, MYC, Myc proto oncogene protein, Proto oncogene c Myc, Transcription factor p64 |
| Immunogen | ：KLH conjugated Synthetic peptide corresponding to Mouse C-MYC |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Predicted MW. | ：49 kDa |
| Observed MW. | ：62 kDa |
| Uniprot ID | ：P01106, P01108, P09416 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 1000 |
brain, lung |
Description
MYC contains one basic helix-loop-helix (bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC.
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Western blot analysis of C-MYC (GB113748) at dilution of 1: 1000 |
Aliases for C-MYC Gene
- GeneCards Symbol: MYC 2
- MYC Proto-Oncogene, BHLH Transcription Factor 2 3 5
- BHLHe39 2 3 4 5
- C-Myc 2 3 5
- MYCC 2 3 5
- V-Myc Avian Myelocytomatosis Viral Oncogene Homolog 2 3
- Class E Basic Helix-Loop-Helix Protein 39 3 4
- Myc Proto-Oncogene Protein 3 4
- Transcription Factor P64 3 4
- Proto-Oncogene C-Myc 3 4
- Myc-Related Translation/Localization Regulatory Factor 3
- Avian Myelocytomatosis Viral Oncogene Homolog 3
- V-Myc Myelocytomatosis Viral Oncogene Homolog 3
- BHLHE39 4
- MRTL 3
