Anti-Artemis Rabbit Polyclonal Antibody
Product#: SB-GB112410
$560.00
Availability:
Ships in 1-2 Weeks
Anti-Artemis Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB112410 |
| Size | ：100 uL |
| Protein full name | ：Protein artemis |
| Synonym | ：MArt, DNA cross-link repair 1C protein, SNM1-like protein, Dclre1c, Art, Snm1l, Artemis protein, SCIDA, SNM1C, ASCID |
| Immunogen | ：Recombinant protein corresponding to Mouse Artemis |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Predicted MW. | ：79 kDa |
| Observed MW. | ：79 kDa |
| Uniprot ID | ：Q8K4J0, Q5XIX3 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 300-1: 600 | kidney, skeletal muscle |
Description
Distinct DNA repair pathways minimize the consequences of mutagenic events. Reactive oxygen species (ROS) are highly reactive atoms with an unpaired electron that are conducive to double-strand DNA breaking events. Artemis, named after the Greek goddess for the protection of children, is one of the major proteins contributing to the preservation of double-strand breaks in DNA by cutting away the damaged parts of the DNA, which allows the strands to rejoin. Artemis is a single-strand-specific 5' to 3' exonuclease that forms a complex with the DNA-dependent protein kinase (DNA-PKcs). DNA-PKcs phosphorylates Artemis, and Artemis acquires endonucleolytic activity on 5' and 3' overhangs and hairpins.
 |
Western blot analysis of Artemis (GB112410) at dilution of 1: 600 Lane 1: Mouse kidney tissue lysate Lane 2: Rat skeletal muscle tissue lysate |
Aliases for DCLRE1C Gene
- GeneCards Symbol: DCLRE1C 2
- DNA Cross-Link Repair 1C 2 3 5
- SNM1C 2 3 4 5
- ARTEMIS 2 4 5
- A-SCID 2 3 5
- SCIDA 3 4 5
- DNA Cross-Link Repair 1C (PSO2 Homolog, S. Cerevisiae) 2 3
- Severe Combined Immunodeficiency, Type A (Athabascan) 2 3
- SNM1-Like Protein 3 4
- Protein Artemis 3 4
- SNM1 Homolog C 3 4
- FLJ11360 2 5
- DNA Cross-Link Repair 1C Protein 4
- PSO2 Homolog (S. Cerevisiae) 2
- Protein A-SCID 4
- EC 3.1.-.- 4
- DCLREC1C 3
- RS-SCID 3
- HSNM1C 4
- ASCID 4
