Anti-Actin Regulatory Protein CAPG/MCP Rabbit Polyclonal Antibody
Anti-Actin Regulatory Protein CAPG/MCP Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB113610 |
| Size | ：100 uL |
| Protein full name | ：Macrophage-capping protein |
| Synonym | ：Actin regulatory protein CAP-G, AFCP, CAPG, MCP, Myc basic motif homolog 1, Mbh1, Actin-capping protein GCAP39, Gelsolin like capping protein, HEL S 66 |
| Immunogen | ：Recombinant protein corresponding to Mouse MCP |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Subcellular location | ：Cell projection, Cytoplasm, Nucleus |
| Predicted MW. | ：39 kDa |
| Observed MW. | ：39 kDa |
| Uniprot ID | ：P24452, Q6AYC4 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 500-1: 1500 |
lung, spleen, kidney |
| IHC | Mouse | 1: 2000-1: 4000 | lung |
Description
CapG (gelsolin-like actin-capping protein) is a member of the gelsolin superfamily proteins, which regulates actin filament length by capping or severing filaments. Studies have shown a role for CapG in regulating cell motility. The expression of CapG is upregulated under hypoxia and in turn increases the motility of cells. Recently it has been reported that the overexpression of CapG is associated with the progression of lung adenocarcinoma as well as lyphatic invasion status of cholangiocarcinoma, which may be used for prognosis of these tumors.
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Western blot analysis of MCP (GB113610) at dilution of 1: 1500 |
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Immunohistochemistry analysis of paraffin-embedded mouse lung using MCP (GB113610) at dilution of 1: 4000 |
Aliases for MCP Gene
- GeneCards Symbol: CAPG 2
- Capping Actin Protein, Gelsolin Like 2 3 5
- MCP 2 3 4 5
- AFCP 3 4 5
- Capping Protein (Actin Filament), Gelsolin-Like 2 3
- Macrophage-Capping Protein 3 4
- Epididymis Secretory Protein Li 66 3
- Actin-Regulatory Protein CAP-G 3
- Actin Regulatory Protein CAP-G 4
- Gelsolin-Like Capping Protein 3
- Macrophage Capping Protein 2
- HEL-S-66 3