Anti-ATF2 Rabbit Polyclonal Antibody (IHC, IF)
Anti-ATF2 Rabbit Polyclonal Antibody (IHC, IF)
General information
| Cat. No. | ：SB-GB11315-1 |
| Size | ：100 uL |
| Protein full name | ：Cyclic AMP-dependent transcription factor ATF-2 |
| Synonym | ：ATF2, CRE-BP1, CREB-2, CREB2, HB16, TREB7, activating transcription factor 2 |
| Immunogen | ：KLH conjugated Synthetic peptide corresponding to Mouse ATF2 |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Subcellular location | ：Nucleus.Cytoplasm.Mitochondrion outer membrane |
| Uniprot ID | ：P16951, Q00969 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| IHC | Mouse, Rat | 1: 500-1: 1000 |
lung cancer, breast cancer, kidney, brain |
| IF | Mouse, Rat | 1: 500-1: 1000 | lung cancer, breast cancer, kidney, brain |
Description
A transcription factor that is a member of the leucine zipper family of DNA binding proteins. The protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation.
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Immunohistochemistry analysis of paraffin-embedded rat brain using ATF2(GB11315-1) at dilution of 1:1000 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using ATF2(GB11315-1) at dilution of 1:1000
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Aliases for ATF2 Gene
- GeneCards Symbol: ATF2 2
- Activating Transcription Factor 2 2 3 4 5
- HB16 2 3 4 5
- CRE-BP1 2 3 5
- TREB7 2 3 5
- CREB2 3 4 5
- Cyclic AMP-Dependent Transcription Factor ATF-2 3 4
- Cyclic AMP-Responsive Element-Binding Protein 2 3 4
- CAMP Response Element-Binding Protein CRE-BP1 3 4
- CAMP-Dependent Transcription Factor ATF-2 3 4
- CREB-2 3 4
- Activating Transcription Factor 2 Splice Variant ATF2-Var2 3
- CAMP Responsive Element Binding Protein 2, Formerly 3
- CAMP Responsive Element Binding Protein 2 2
- CAMP-Responsive Element-Binding Protein 2 4
- Histone Acetyltransferase ATF2 3
- CREBP1 4
