Anti Mouse G9a /Ehmt2 mouse monoclonal antibody (A8620A)
General information
| Cat. No. |
:FNK-PP-A8620A-00 |
| Size |
:100 ul |
| Purification |
:Ammonium sulfate fractionation |
| Clone No |
:A8620A |
| Lot. |
:A-2 |
| Concentration |
:1 mg/mL |
| Ig Class |
:G2a |
| Epitope |
:– |
| Application |
:ELISA ( 0.1 ug/mL),Western Blot (0.5 ug/mL), Immunohistochemistry (5 ug/mL) |
| Specificity |
:This antibody specifically recognizes mouse G9a and cross reacts with human G9a.
Not yet tested in other species.
|
| Storage |
:Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form |
:Physiological saline with 0.1% NaN3 as a preservative. |
| Genbank |
:AB077209 |
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant mouse G9a (15-114aa) .
Description
Histone H3 Lys 9 (H3-K9) methylation is a crucial epigenetic mark for transcriptional silencing. G9a is the major mammalian H3-K9 methyltransferase that targets euchromatic regions and is essential for murine embryogenesis.
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Reference
1. Tachibana M. et al., Genes Dev, 1; 19(7): 815-26, 2005.
Aliases for EHMT2 Gene
- Euchromatic Histone Lysine Methyltransferase 2 2 3 5
- KMT1C 2 3 4
- G9A 2 3 4
- Euchromatic Histone-Lysine N-Methyltransferase 2 3 4
- Histone-Lysine N-Methyltransferase EHMT2 3 4
- Histone H3-K9 Methyltransferase 3 3 4
- HLA-B Associated Transcript 8 2 3
- Lysine N-Methyltransferase 1C 3 4
- H3-K9-HMTase 3 3 4
- C6orf30 3 4
- BAT8 3 4
- NG36 3 4
- Histone-Lysine N-Methyltransferase, H3 Lysine-9 Specific 3 3
- Chromosome 6 Open Reading Frame 30 2
- Ankyrin Repeat-Containing Protein 3
- G9A Histone Methyltransferase 3
- HLA-B-Associated Transcript 8 4
- Em:AF134726.3 2
- Protein G9a 4
- EC 2.1.1.- 4
- NG36/G9a 2
- EHMT2 5
- GAT8 3