Anti Human PR isoform B mouse monoclonal antibody (H5344)
Product#: FNK-PP-H5344-00
$501.52
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Anti Human PR isoform B mouse monoclonal antibody (H5344)
PR isoform B: Progesterone Receptor isoform B
General information
| Cat. No. | ：FNK-PP-H5344-00 |
| Size | ：100 ul |
| Antigen Species | ：Human |
| Host Species | ：Mouse |
| Cross Reactivity | ：Human |
| Purification | ：Ammonium sulfate fractionation. |
| Clone No | ：H5344 |
| Lot. | ：A-1 |
| Concentration | ：1 mg/mL |
| Ig Class | ：G2a |
| Nomenclature | ：NR3C3 |
| Application | ：ELISA : 0.3 ug/mL (A450=0.5) ：Western Blot : 1 ug/mL ：Non reducing Western Blot: 3 ug/mL ：Immunohistochemistry: 10-20 ug/mL |
| Specificity |
：This antibody specifically recognizes human PR isoform B and cross reacts with mouse and rat
PR isoform B. This antibody does not recognize human PR isoform A. |
| Storage | ：Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | ：Physiological saline with 0.1% NaN3 as a preservative |
| Genbank | ：M15716 |
Description
Progesterone receptor (PR; NR3C3) is a member of steroid receptor (GR, AR, MR, ER). PR binds progesterone. PR is expressed in uterus, ovary, vagina, fallopian tubes and breast. PR plays a central role in diverse reproductive events associated with establishment and maintenance of pregnancy, alveolar development in the breast, and sexual behavior. Two isoforms of this receptor have been identified, PR-A and PR-B, 94 and 114 kDa in size, respectively. PR was shown that PR-A and PR-B isoforms can form homodimers as well as heterodimers.
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human PR isoform B (2-99 aa) .
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Aliases for PGR Gene
