4-Methoxyphenyl β-D-glucopyranoside

4-Methoxyphenyl β-D-glucopyranoside
 

• CAT Number : FNK-GL002005
• CAS Number : 6032-32-2
• Molecular Weight : 286.28
• Molecular Formula : C₁₃H₁₈O₇
• Pack size: 5 g
• Store: 2－10 ℃
• Purity: >98%(HPLC)

Product Description
4-Methoxyphenyl β-D-glucopyranoside is a synthetic glycoside consisting of a glucose molecule linked to a 4-methoxyphenyl group. It is likely used as a model compound in carbohydrate chemistry research and glycobiology studies.

Property

• Chemical Formula: C₁₃H₁₈O₇ 
• Molecular Weight: Approximately 286.28 g/mol
• Appearance: Likely a white to off-white crystalline powder
• Solubility: Probably soluble in water and polar organic solvents

Application and Usage

• Research: Used in studies investigating glycoside chemistry and enzyme kinetics
• Analytical Standard: May serve as a reference compound in carbohydrate analysis
• Biochemical Studies: Potentially used to study glycoside hydrolases and other carbohydrate-active enzymes

Safety and Handling

• Storage: Store in a cool, dry place, protected from light
• Handling: Use appropriate personal protective equipment
• Safety Measures: For research use only; not for human consumption without proper testing and approval

Involved Human Diseases

• Neurological Disorders
  • Alzheimer's Disease: Research suggests that this compound may be relevant to Alzheimer's disease, particularly through its action on beta-amyloid. Its neuroprotective properties could potentially help mitigate the progression of neurodegenerative processes.
  • Parkinson's Disease: While not directly studied, the neuroprotective effects observed with similar compounds suggest potential benefits for Parkinson's disease as well
• Metabolic Disorders
  • Diabetes: Studies have indicated beneficial effects on diabetic mice models. The compound may play a role in regulating glucose metabolism and improving insulin sensitivity.
• Cardiovascular Diseases

• Inflammatory Conditions
  • The anti-inflammatory properties of 4-methoxyphenyl β-D-glucopyranoside and similar phenolic compounds may be beneficial in treating various inflammatory diseases. These effects are likely mediated through the inhibition of pro-inflammatory cytokines and modulation of key inflammatory pathways such as NF-κB, MAPK, and NLRP3.
• Cancer
  • While not extensively studied, some research indicates potential anticancer effects. The compound may induce cell cycle arrest in cancer cells, suggesting a possible role in cancer treatment or prevention.

Cell Signaling Pathways Affected

• Protein Kinase A (PKA) Signaling Pathway
  •    Activation of PKA in the liver
  •    Potential promotion of lipid breakdown through PPARα activation
• Calpain1/PKA/CREB Pathway
  •    Phosphorylation of CREB
  •    Increased expression of PKA RII
  •    Associated with neuroprotective effects and increased glucose uptake
• Apoptosis-Related Pathways
  •    Restoration of pro- and anti-apoptotic protein balance
  •    Inhibition of caspase-3 and PARP activation
• Oxidative Stress Pathways
  •    Antagonism of reactive oxygen species (ROS) generation
  •    Inhibition of iNOS-derived NO production
• G Protein-Coupled Receptor (GPCR) Signaling
  •    Potential interaction with GPCRs such as GPR41
  •    Possible modulation of various GPCR-associated cellular signaling cascades